Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5214086 | Tetrahedron | 2016 | 8 Pages |
Abstract
In this article, a number of novel brominated heterocycles based on aminobromopyrrolone, bromopyridazinone and hydrazinyl furanone scaffolds were synthesized from the reactions of brominated furanones with bi-nucleophiles, such as substituted or unsubstituted hydrazines. Some of these compounds were found to be effective quorum sensing (QS) inhibitors against Pseudomonas aeruginosa.
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