| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5214120 | Tetrahedron | 2015 | 8 Pages |
Abstract
Recent studies of diastereoselective conjugate additions of monoorganocuprates, Li[RCuI], to chiral γ-alkoxycrotonates and fumarates are disclosed. This methodology was applied to the shortest total synthesis of (−)-dihydroprotolichesterinic acid to date, but several attempts to prepare other succinate-derived natural products, such as pilocarpine and antrodin E, were unsuccessful.
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