Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5214347 | Tetrahedron | 2015 | 15 Pages |
Abstract
The present study focused on synthesizing bolaamphiphiles from the readily available and inexpensive castor oil, a vegetable oil, which contains about 90% of ricinoleic acid. Two classes of symmetric and asymmetric bolaamphiphiles with acetylcholine head groups were synthesized and characterized by spectroscopic analysis. These novel bolaamphiphilic compounds self-assemble in aqueous media to form stable cationic spherical nano-sized vesicles that are potential drug delivery systems.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Monique B. Ewonkem, Sarina Grinberg, Gabriel Lemcoff, Eleonora Shaubi, Charles Linder, Eliahu Heldman,