Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5214642 | Tetrahedron | 2015 | 11 Pages |
Abstract
A flexible route to piperidine-2,4-diones variously substituted at the 6-, 5,6- and 2,6-positions, both with and without 1-substitution, is described; no N-protective group is required. A related regioselective Dieckmann cyclisation is also described that uses Davies' α-methylbenzylamine auxiliary and affords 6-substituted piperidine-2,4-diones enantioselectively.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Charles M. Marson, Kin Cheung Yau,