Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5214872 | Tetrahedron | 2015 | 8 Pages |
Abstract
A new and mild synthetic approach for the synthesis of N-arylsulfonamides under copper-catalyzed conditions at room temperature has been developed. The reaction employs various tert-butyl N-sulfonylcarbamates and diaryliodonium salts to avoid potential genotoxic impurities. A one-pot coupling/Boc-deprotection sequence is also reported to provide mono N-arylsulfonamides in good to excellent yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Soo-Yeon Moon, Moonjee Koh, Kris Rathwell, Seo-Hee Jung, Won-Suk Kim,