Article ID Journal Published Year Pages File Type
5215006 Tetrahedron 2015 6 Pages PDF
Abstract

A novel amide bond formation reaction was developed via N-heterocyclic carbene (NHC)-catalysed direct amidation of vinyl esters. In the presence of 5.0 mol % NHC catalyst, a variety of aromatic amines undergo acylation reaction with different vinyl esters to produce amides in 51% to quantitative yields.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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