Article ID Journal Published Year Pages File Type
5215154 Tetrahedron 2015 14 Pages PDF
Abstract

Herein we report the full details of our efforts toward the application of Pauson-Khand reaction for the stereoselective construction of the trans-decalin subunit with a C16 quaternary stereocenter of fusarisetin A, which led to the asymmetric total synthesis of (+)-fusarisetin A. The developed chemistry provides an alternative strategy to the intramolecular Diels-Alder reaction that has been employed for the synthesis of trans-decalin based natural products.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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