Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215154 | Tetrahedron | 2015 | 14 Pages |
Abstract
Herein we report the full details of our efforts toward the application of Pauson-Khand reaction for the stereoselective construction of the trans-decalin subunit with a C16 quaternary stereocenter of fusarisetin A, which led to the asymmetric total synthesis of (+)-fusarisetin A. The developed chemistry provides an alternative strategy to the intramolecular Diels-Alder reaction that has been employed for the synthesis of trans-decalin based natural products.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jun Huang, Lichao Fang, Jianxian Gong, Chuangchuang Li, Zhen Yang,