Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215211 | Tetrahedron | 2015 | 5 Pages |
Abstract
N-(2-Chloro-phenyl)-2-halo-benzamides (halo=I/Br/Cl) as substrates were used for the one-pot synthesis of 2-arylbenzoxazole derivatives via copper-catalyzed intermolecular C-N/intramolecular C-O couplings with primary amines. This aryl amination offers clean reaction conditions and easy work-up in good yields by using CuI as catalyst, readily available 8-hydroxyquinoline as ligand, K3PO4 as base, DMF as solvent.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Dazhuang Miao, Xuesong Shi, Guozhen He, Yao Tong, Zengqiang Jiang, Shiqing Han,