| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5215301 | Tetrahedron | 2015 | 6 Pages |
Abstract
An efficient and convenient method was developed for the synthesis of β-amino-α-fluoro-sulfides in one-step from corresponding β-amino-sulfides by using N-iodosuccinimide (NIS) and diethylaminosulfur trifluoride (DAST) as a fluoride source. This fluorination method was verified on various β-amino-sulfides substrate contained different function groups, such as N-phthalimide (NPhth), N-acetyl, N-benzoyl, N-(tert-butyl carbamate) (N-Boc), N-(benzyl carbamate) (N-Cbz), and methoxycarbonyl substitution groups.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hongju Chen, Zhanxing Hu, Jianxin Zhang, Guangyi Liang, Bixue Xu,