Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215322 | Tetrahedron | 2015 | 7 Pages |
Abstract
Two hydroxychavicol heterodimers comprising phenylpropanoid and monoterpene constituent units, named nudibaccatumins A (1) and B (2), were isolated as an inseparable mixture from the aerial parts of Piper nudibaccatum. Their absolute configurations were confirmed by total synthesis using ortho-alkylation of hydroxychavicol with myrtenyl bromide as the key reaction. The two new compounds (1 and 2) and their synthetic analogues (3-8) were evaluated for XO inhibitory activity.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hong-Xin Liu, Hai-Bo Tan, Meng-Ting He, Ling Li, Yue-Hu Wang, Chun-Lin Long,