Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215366 | Tetrahedron | 2015 | 9 Pages |
Abstract
A possible synthetic approach to the bridged indole alkaloid pericine (subincanadine E), based on the combination of a ring-closing metathesis (RCM) and a Heck cyclization, is described. After having developed a convenient RCM-based route to tricyclic intermediates embodying the central nine-membered ring, the closure of the strained 1-azabicyclo[5.2.2]undecane framework of the alkaloid using a vinyl halide Heck coupling was pursued without success.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
M.-Lluïsa Bennasar, Daniel Solé, Tomà s Roca, Magdalena Valldosera,