Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215386 | Tetrahedron | 2015 | 5 Pages |
Abstract
An efficient and practical method for macrocyclic lipoglycopeptide synthesis was developed and utilized to synthesize lipoglycosylated derivatives of Tyrocidine A. The method is based on solid-phase peptide synthesis using 2-chlorotrityl resin as the solid-phase support and lipoglycosyl amino acids as building blocks. This synthetic method should be generally applicable to various macrocyclic lipoglycopeptides.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Qingjie Zhao, Xiang Li, Wenjuan Li, Yan Zou, Honggang Hu, Qiuye Wu,