Article ID Journal Published Year Pages File Type
5215386 Tetrahedron 2015 5 Pages PDF
Abstract

An efficient and practical method for macrocyclic lipoglycopeptide synthesis was developed and utilized to synthesize lipoglycosylated derivatives of Tyrocidine A. The method is based on solid-phase peptide synthesis using 2-chlorotrityl resin as the solid-phase support and lipoglycosyl amino acids as building blocks. This synthetic method should be generally applicable to various macrocyclic lipoglycopeptides.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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