Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215442 | Tetrahedron | 2014 | 7 Pages |
Abstract
A novel base-promoted O-deprotonation/alkylation reaction of P(O)–OH compounds with alkyl halides has been developed. The protocol is practical, representing a simple way to produce a broad spectrum of functionalized phosphinates, phosphonates, and phosphates from basic starting materials with good to excellent yields. A plausible mechanism was proposed for this reaction.
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