Article ID Journal Published Year Pages File Type
5215442 Tetrahedron 2014 7 Pages PDF
Abstract

A novel base-promoted O-deprotonation/alkylation reaction of P(O)–OH compounds with alkyl halides has been developed. The protocol is practical, representing a simple way to produce a broad spectrum of functionalized phosphinates, phosphonates, and phosphates from basic starting materials with good to excellent yields. A plausible mechanism was proposed for this reaction.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry