Article ID Journal Published Year Pages File Type
5215446 Tetrahedron 2014 9 Pages PDF
Abstract

A total synthesis of Daphnodorin A, a member of the Daphnodorins, was accomplished. Key features of the synthetic strategy include construction of 2-substituted-3-functionalized benzofuran via intramolecular Heck reaction and a mild Barton-McCombie deoxygenation process mediated by triethylborane. The total synthesis provided Daphnodorin A in 19.7% or 5.6% overall yield over 7 or 15 steps.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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