Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215542 | Tetrahedron | 2014 | 5 Pages |
Abstract
Mild methods for the deprotection of organic substrates are of fundamental importance in synthetic chemistry. A new room temperature method using a catalytic amount of Cu(OTf)2 is reported. This allows use of the tert-butyl group as an amide protecting group. The methodology is also extended to Boc-deprotection.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry