Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215560 | Tetrahedron | 2014 | 6 Pages |
Abstract
A few phosphinic acids, such as phenylphosphinic acids, 1-hydroxy-3-phospholene 1-oxides and 1-hydroxyphospholane oxides are esterified with simple alcohols in the presence of propylphosphonic anhydride (T3P®). If 1.1 equiv of the T3P® reagent is used, the esterifications are fast and efficient at 25° C. In the case of more reactive models it was enough to apply 0.66 equiv of T3P® at 85° C under microwave conditions. The amidation of 1-hydroxy-3-methyl-3-phospholene oxide could also be accomplished under similar conditions.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Erzsébet Jablonkai, Réka Henyecz, Mátyás Milen, János Kóti, György Keglevich,