| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5215569 | Tetrahedron | 2014 | 7 Pages |
Abstract
Cyclocondensation of salicylaldehydes with alkyl acetoacetates and 2-aminobenzothiazoles or 2-amino-5-methylthiazole under classical Biginelli reaction conditions gives rare hetarylamino substituted 2,2′-spirobischromanecarboxylate derivatives. The mechanism and observed stereoselectivity of the unexpected pseudo-four-component process are discussed.
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