Article ID Journal Published Year Pages File Type
5215597 Tetrahedron 2015 6 Pages PDF
Abstract

A FeCl3-catalyzed multicomponent reaction was developed for the facile synthesis of coumarin-3-carboxylic ester derivatives in a highly atom-economic and environmentally friendly way. Using simple and cheaply available salicylaldehydes, Meldrum's acid and alcohols as the starting materials, the method needs no extra additives and features wide substrate scope, good functional group tolerance and mild reaction conditions.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry