Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215691 | Tetrahedron | 2014 | 7 Pages |
Abstract
A general and efficient P(V)-N activation method for the preparation of symmetrical and asymmetrical dinucleoside polyphosphates (NpnNâ²s, n=2-4) and P2,P3-CX2-dinucleoside tetraphosphates (X=H, F, and Cl) has been established. Twenty-two dinucleoside polyphosphates and their phosphonate analogs were synthesized from nucleoside 5â²-phosphoropiperidates with 4,5-dicyanoimidazole as the activator in good to high yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Qi Sun, Shan-Shan Gong, Si Liu, Jian Sun, Guo-Dong Liu, Cha Ma,