| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5215727 | Tetrahedron | 2014 | 5 Pages |
Abstract
A new approach to 3-(diethoxyphosphoryl)-4-(2-oxoalkyl)-3,4-dihydrocoumarins by base promoted conjugate addition of enolizable ketones to 3-(diethoxyphosphoryl)coumarin is described. The resulting products were transformed into the corresponding α-methylene-δ-lactones. A transition state model rationalizing stereochemical outcome of the reaction is proposed.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
