Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215754 | Tetrahedron | 2015 | 12 Pages |
Abstract
This study describes the palladium-catalyzed couplings of iodopyridines, chloropyridines, and chloroquinoline with atom-economic BiAr3 reagents in sub-stoichiometric loadings. Mono-arylations of iodo and chloropyridines produced arylpyridines in high yields. The couplings addressed with dihalopyridines have afforded chemo- and regio-selective coupling products. Arylations of 2-chloroquinoline with different triarylbismuth reagents demonstrated fruitful coupling reactivity under the established conditions. This sumptuous study demonstrates the remarkable cross-coupling reactivity of iodo/chloropyridines and chloroquinoline with triarylbismuth reagents.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Maddali L.N. Rao, Ritesh J. Dhanorkar,