Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215815 | Tetrahedron | 2014 | 6 Pages |
Abstract
Eleven Lycopodium alkaloids with lycodine-type, lycopodine-type, and fawcettimine-related skeletons were isolated from the whole plants of Huperzia carinata (Desv. Ex. Poir.) Trevis and Huperzia squarrosa (G. Forst) Trevis (Huperziaceae). Among them, 8,15-dihydrohuperzine A (2), lycocarinatine A (3), and lycoposerramine U N-oxide (11) are new compounds. The structures of these new alkaloids were elucidated on the basis of 2D NMR correlations. Some of these isolated alkaloids were assayed for acetylcholinesterase (AChE) inhibitory activity.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sakornrat Thorroad, Prateep Worawittayanont, Nisachon Khunnawutmanotham, Nitirat Chimnoi, Apiwan Jumruksa, Somsak Ruchirawat, Nopporn Thasana,