Article ID Journal Published Year Pages File Type
5215969 Tetrahedron 2014 7 Pages PDF
Abstract

An improved preparation of a functionalized 2,8-ethanonoradamantane derivative, which avoids two protection/deprotection steps while deprotection of a benzyloxymethyl protecting group takes place during an acid-catalyzed dehydration, is described. Altogether the synthesis has been reduced in five steps (from 16 to 11 steps) with an increase in the global yield from 5.8 to 7.2%.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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