Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215969 | Tetrahedron | 2014 | 7 Pages |
Abstract
An improved preparation of a functionalized 2,8-ethanonoradamantane derivative, which avoids two protection/deprotection steps while deprotection of a benzyloxymethyl protecting group takes place during an acid-catalyzed dehydration, is described. Altogether the synthesis has been reduced in five steps (from 16 to 11 steps) with an increase in the global yield from 5.8 to 7.2%.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Pelayo Camps, TÃ nia Gómez, Ane Otermin,