Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5215981 | Tetrahedron | 2014 | 8 Pages |
Abstract
Enantiomerically pure β-lactams bearing a Weinreb amide functionality at the C3 position have been shown to be excellent substrates for α-alkylation reactions, generating C3 quaternary centers with predictable absolute stereochemistry. In addition, oxidative coupling of C3/C4 dianions affords entry to fused β,γ-bislactam systems.
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