Article ID Journal Published Year Pages File Type
5216176 Tetrahedron 2014 5 Pages PDF
Abstract

An efficient synthesis of tenuifoliside B, which shows potential cognitive improvement and cerebral protective effects that may be further developed to become an anti-AD lead compound, has been developed starting from commercial available starting materials. Regioselective introductions of acyl groups to the OH-3′ and OH-6 of sucrose play the key steps by metal chelate-directed acylation and Mitsunobu esterification, respectively.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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