Stereoselective synthesis of erythro-β-chloroamines and their conversion into functionalized trans-oxazolidin-2-ones

New erythro-β-chloroamines were synthesized by a mild and efficient stereoselective chlorination of unprotected amino alcohol diesters. These products are shown to be excellent building blocks for the synthesis of new substituted trans-oxazolidin-2-ones.

Graphical abstractDownload full-size image