| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5216326 | Tetrahedron | 2014 | 6 Pages |
Abstract
A mild, redox neutral photocatalytic method for alkene hydrothiolation is reported. Utilizing visible-light activation, catalytic radical initiation is achieved with the transition metal complex Ru(bpy)3Cl2, enabling rapid access to a diverse set of thiol-ene coupled products in excellent yield. On the basis of a strong observed background reaction in some cases, we have developed a solvent-free, Lewis acid-promoted tandem amidation-hydrothiolation sequence, providing thiomorpholin-3-ones in a one-pot operation from commercially available materials.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mitchell H. Keylor, James E. Park, Carl-Johan Wallentin, Corey R.J. Stephenson,