| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5216343 | Tetrahedron | 2014 | 8 Pages |
Abstract
The relative cleavage of an alcohol from a panel of amino esters and amino carbonates via intramolecular cyclization was examined as a mechanism for substrate release. Thermal stability at 37 °C was observed only for the seven-membered ring progenitors. Applicability of the approach was illustrated by δ-lactam formation within a poly(dimethylsiloxane) microchannel for release of a captured fluorescent probe.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ralph J. Knipp, Rosendo Estrada, Palaniappan Sethu, Michael H. Nantz,