Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5216392 | Tetrahedron | 2014 | 7 Pages |
Abstract
Treatment of ethyl 4-aryl-6-(trifluoromethyl)-2-oxo-2H-pyran-3-carboxylates, prepared from 4,4,4-trifluorobutane-1,3-diones, PCl5Â and sodium diethyl malonate, with sulfuric acid afforded the intramolecular Friedel-Crafts acylation products, 3-(trifluoromethyl)indeno[2,1-c]pyran-1,9-diones, from which 2-(trifluoromethyl)-6H-pyrano[3,4-c]quinoline-4,5-diones were obtained via the Schmidt reaction in moderate yields. The latter reacted with sodium azide to give 2-oxo-4-(5-trifluoromethyl-1,2,3-triazol-4-yl)-1,2-dihydroquinoline-3-carboxylic acids in good yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sergey A. Usachev, Boris I. Usachev, Vyacheslav Ya. Sosnovskikh,