Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5216411 | Tetrahedron | 2014 | 7 Pages |
Abstract
A facile and stereocontrolled construction of optically active pyrazinoisoquinoline skeletons based on tandem cyclization of enantiopure phenylalanine derivatives was examined. The reaction provided optically active 6,11b-trans pyrazinoisoquinoline ring systems in excellent diastereoselectivity, and this method was applicable to the cyclization of phenylalanine derivatives with diverse substituents.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Maki Seki, Tsuyoshi Ogiku,