| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5216473 | Tetrahedron | 2013 | 9 Pages |
Abstract
The Lewis acid-catalyzed regioselective azidolysis of 2,3-three membered heterocyclic amines has been investigated. The results obtained demonstrated that using TMSN3 as a source of azide, the appropriate choice of Lewis acid allowed to obtain different regio- and stereocontrolled precursors of aminoalcoholic and triaminic sequences. Considering the occurrence of these moieties in the structure of many biologically active compounds, the present methodologies could represent a powerful tool in organic synthesis for the preparation of interesting molecules.
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Physical Sciences and Engineering
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