| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5216581 | Tetrahedron | 2014 | 8 Pages |
Abstract
An efficient and simple method for the synthesis of 2-unsubstituted 1-aryl-4- and 1-aryl-5-acylimidazoles has been developed. It consists in the condensation of α-diketone monooximes with aromatic amines and formaldehyde on the presence of boron trifluoride etherate, leading to the formation of stable boron trifluoride complexes of N-oxides. Further reduction of these complexes led to the corresponding imidazoles. This method permits broad variations of substituents in the aryl part of these compounds.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
