Article ID Journal Published Year Pages File Type
5216632 Tetrahedron 2014 8 Pages PDF
Abstract

A facile one-pot synthetic route for preparing a series of functionalized diarylcyclopropyl spirocyclic ketones 4 is developed. The efficient cyclopropanation route of the conjugated cyclic ketones 2 with sulfones 1 in the presence of NaH shows interesting molecular diversities. The reaction mechanism of the stereocontrolled cyclopropanations has been discussed.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry