Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5216632 | Tetrahedron | 2014 | 8 Pages |
Abstract
A facile one-pot synthetic route for preparing a series of functionalized diarylcyclopropyl spirocyclic ketones 4 is developed. The efficient cyclopropanation route of the conjugated cyclic ketones 2 with sulfones 1 in the presence of NaH shows interesting molecular diversities. The reaction mechanism of the stereocontrolled cyclopropanations has been discussed.
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