Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5216659 | Tetrahedron | 2014 | 5 Pages |
Abstract
Highly diastereo- and enantioselective conjugate addition of 3-aryloxindoles to maleimide was accomplished under base-free phase-transfer conditions. The effect of Brønsted acid co-catalyst was examined, and we found that the use of a phenol derivative as co-catalyst was effective for obtaining the target conjugate adduct in good yield with high stereoselectivity.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Seiji Shirakawa, Hiroki Makino, Tomofumi Yoshidome, Keiji Maruoka,