Article ID Journal Published Year Pages File Type
5216664 Tetrahedron 2014 9 Pages PDF
Abstract

The direct imine acylation (DIA) and subsequent cyclisation of a range of imines with ortho-substituted benzoic acid derivatives is described. Variation in the coupling reagents, imine and benzoic acid were all examined. The DIA procedure was also applied in the total synthesis of (±)-cavidine.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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Substrate scope in the direct imine acylation of ortho-substituted benzoic acid derivatives: the total synthesis (±)-cavidine
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