Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5216723 | Tetrahedron | 2014 | 5 Pages |
Abstract
Magnetic Fe3O4 nanoparticles as a heterogeneous catalyst, were found to be efficient for the synthesis of a series of pyranopyrazoles by a four component reaction of a mixture of hydrazine hydrate, ethyl acetoacetate, aldehydes/ketones and malononitrile in water at room temperature. The products were attributed to the nanosize of about 16Â nm in which the catalyst could act as a nanoreactor. The present protocol offers the advantages of clean reaction, short reaction time, high yield, easy purification and economic availability of the catalyst.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mahmoud. Abd El Aleem. Ali. Ali. El-Remaily,