| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5216754 | Tetrahedron | 2013 | 6 Pages |
Abstract
Efficient and applicable approach to macrolactonizations, with ready availability of starting materials and simple operation, remains a challenging task for the organic community. We developed a 'freshman-can-do' protocol to medium- and large-sized lactones, not depending on high-dilution or slow addition techniques. Application of this method for the synthesis of natural lactones or potentially pharmaceutical compounds might be useful for organic chemists and pharmacists.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Le Liu, Shimin Xu, Hongwei Zhou,