Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5216765 | Tetrahedron | 2013 | 7 Pages |
Abstract
The sodium salts of the conjugated bases of uracils undergo highly chemoselective O4-monoalkylation when treated with various alkyl halides in dry DMF, while the use of methyl iodide results in N1+N3-dimethylation. Theoretical evaluations of the chemo- and regioselectivity along with X-ray crystallographic data are presented.
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