| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5216789 | Tetrahedron | 2014 | 9 Pages |
Abstract
A simple method for the synthesis of sugar-derived imines by a Schwartz's reagent reduction of easily available sugar lactams has been described. A direct addition of nucleophiles to the generated in situ cyclic imines and subsequent deprotection of hydroxyl function allows to convert sugar lactams in polyhydroxylated pyrrolidines and piperidines.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Piotr SzczeÅniak, Sebastian Stecko, Olga Staszewska-Krajewska, BartÅomiej Furman,