| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5216844 | Tetrahedron | 2014 | 7 Pages |
Abstract
By employing a chiral bifunctional thiourea-tertiary amine as catalyst, enantioselective tandem Michael addition-oxidation of 3-monosubstituted oxindoles with 1,4-benzoquinones were realized. The reactions afforded a wide range of 3,3-disubstituted oxindoles with moderate to good yields (up to 87%) in moderate to good enantioselectivities (up to 96%).
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yonghong Zhang, Xiaoyan Hu, Shuaishuai Li, Yijun Liao, Weicheng Yuan, Xiaomei Zhang,