| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5216885 | Tetrahedron | 2014 | 6 Pages |
Abstract
Dimethyl maleate was found to be a very reactive and selective acceptor for the aza-Michael addition in comparison to other commonly used electron-deficient alkenes. It reacts efficiently with a variety of aliphatic amines in complete absence of any catalyst and solvent at room temperature. Under these environmentally-friendly conditions, high yields of selectively mono-adducts were obtained within short reaction times.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Giovanna Bosica, Anthony John Debono,