| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5216887 | Tetrahedron | 2014 | 7 Pages |
Abstract
A Lewis acid-catalyzed [3+1+1] cycloaddition reaction between aliphatic isocyanides and azomethine ylides generated in situ from aziridines, leading to pyrrolidine derivatives, has been developed. This reaction proceeds smoothly under mild conditions and can also be modified by employing aromatic isocyanides to generate four-membered heterocycles, azetidines, through a [3+1] cycloaddition reaction.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
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