| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5216914 | Tetrahedron | 2013 | 6 Pages |
Abstract
The Receptor for Advanced Glycation Endproducts ('RAGE') mediates transport of amyloid-β peptide (Aβ) into the brain, and is therefore an important target for the development of therapeutic agents for Alzheimer's disease. We describe structure-activity relationships for inhibition of RAGE-Aβ binding, derived from the analysis of a library of tertiary amides.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nathan T. Ross, Rashid Deane, Sheldon Perry, Benjamin L. Miller,