Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5216927 | Tetrahedron | 2013 | 12 Pages |
Abstract
A chemo- and diastereoselective iron-catalyzed cross-coupling between C-bromo mannopyranoside derivatives and 2-methyl-1-propenylmagnesium bromide was developed. This method was used as the key step for the synthesis of the mirror image of the C31-C40 and C43-C52 fragments of amphidinol 3 (AM3). These syntheses were achieved from a common trans-tetrahydropyran derived from d-mannose.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Charlélie Bensoussan, Nicolas Rival, Gilles Hanquet, Françoise Colobert, Sébastien Reymond, Janine Cossy,