Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5216934 | Tetrahedron | 2013 | 9 Pages |
Abstract
Tethering additional functionality to cyclobutadienyl iron tricarbonyl complexes provides new opportunities for the rapid construction of medium-ring-containing polycyclic compounds. Specifically, an intramolecular cycloaddition between cyclobutadiene and a tethered olefin, followed by an intramolecular cyclopropanation of the resulting cyclobutene-containing adduct generates highly strained pentacyclic intermediates. These compounds can then be relaxed thermally to generate 5-7-5 and 5-7-6 fused tricyclic ring systems that are shared with numerous natural products.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jing He, Marc L. Snapper,