Article ID Journal Published Year Pages File Type
5216934 Tetrahedron 2013 9 Pages PDF
Abstract

Tethering additional functionality to cyclobutadienyl iron tricarbonyl complexes provides new opportunities for the rapid construction of medium-ring-containing polycyclic compounds. Specifically, an intramolecular cycloaddition between cyclobutadiene and a tethered olefin, followed by an intramolecular cyclopropanation of the resulting cyclobutene-containing adduct generates highly strained pentacyclic intermediates. These compounds can then be relaxed thermally to generate 5-7-5 and 5-7-6 fused tricyclic ring systems that are shared with numerous natural products.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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