Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5217021 | Tetrahedron | 2014 | 5 Pages |
Abstract
A novel silver-catalyzed tandem reaction of 2-alkynylbenzaldoximes with H-phosphinate esters, and H-phosphine oxides has been developed, providing a general and powerful tool for the synthesis of various 1-phosphorylated isoquinolins in moderate to excellent yield. This reaction proceeded smoothly to construct C–N and C–P bonds in one-pot with good functional group tolerance under mild conditions.
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