| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217072 | Tetrahedron | 2014 | 15 Pages |
Abstract
With a goal of the total synthesis of polymaxenolide, the first hybrid marine natural product, the model studies for constructing the dihydropyran portion based on the originally proposed biosynthesis (C-C bond formation followed by dehydrative cyclization) and the synthesis of the lower portion (the C1-C3, C7-C17 portion) based on an iodide-induced Morita-Baylis-Hillman type reaction (a three-component assembly) followed by Suzuki-Miyaura cross-coupling are described.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yutaka Matsuda, Masaya Kato, Tomonori Kawaguchi, Takayuki Koyama, Yoko Saikawa, Masaya Nakata,