| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217138 | Tetrahedron | 2014 | 6 Pages |
Abstract
Six new indole alkaloids, hyrtimomines F-K (1-6), were isolated from Okinawan marine sponges Hyrtios spp. The structures of 1-6 were elucidated on the basis of spectroscopic analysis. Hyrtimomine F (1) is a structurally unique bisindole alkaloid possessing an α-keto-É-caprolactam ring, while hyrtimomine G (2) is a symmetrical bisindole alkaloid. Hyrtimomines H-K (3-6) are indole alkaloids possessing β-carboline skeleton with an imidazolium unit. Antimicrobial activities of hyrtimomines F-K (1-6) were evaluated.
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Physical Sciences and Engineering
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Organic Chemistry
Authors
Naonobu Tanaka, Rei Momose, Azusa Takahashi-Nakaguchi, Tohru Gonoi, Jane Fromont, Jun'ichi Kobayashi,