| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217151 | Tetrahedron | 2014 | 5 Pages |
Abstract
The Mg-activation of benzal bromide 2b in DMF in the presence of carbonyl compounds 1 or imines 4 leads to epoxides 3 and N-arylaziridines 5, respectively, with acceptable isolated yields. It was found that DMF is likely involved in this process to form a nucleophilic intermediate by reaction with a first generated electrophilic carbene. Results obtained in this chemical approach are compared to those obtained using electrochemical activation, also in DMF.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sylvain Oudeyer, Eric Léonel, Jean Paul Paugam, Jean-Yves Nédélec,