| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5217174 | Tetrahedron | 2014 | 5 Pages |
Abstract
A facile and efficient one-pot three-component synthesis of spiroazepinoindolones has been developed. Using DMF as solvent without any additional acid or metal catalysts, the three-component reaction of readily available isatins, indolamines, and Meldrum's acid affords a new class of spiroheterocycles in moderate yield.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![An efficient synthesis of 4,6-dihydrospiro[azepino[4,3,2-cd]indole-3,3â²-indoline]-2â²,5(1H)-diones via multi-component reaction](/preview/png/5217174.png "First Page Preview: An efficient synthesis of 4,6-dihydrospiro[azepino[4,3,2-cd]indole-3,3â²-indoline]-2â²,5(1H)-diones via multi-component reaction")
Authors
Bin Zou, Chun Chen, Seh Yong Leong, Mei Ding, Paul W. Smith,